ab12969 Antizyme inhibitor 1 Antibody
品牌 |
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产品货号 |
ab12969 |
来源种属 |
Rabbit |
抗体克隆 |
Polyclonal |
来源亚型 |
IgG |
实验方法 |
WB,IHC |
实验种属 |
Human,Mouse,Rat,Rabbit,Pig,Dog,Chicken,Bovine,Horse,Sheep |
偶联标记 |
Unconjugated |
目的蛋白 |
Antizyme inhibitor 1 |
产品规格 |
50μl,100μl,200μl |
产品报价 |
¥1500/¥2750/¥3600 |
实验应用
Western blotting
Recommended dilution: 1:500-1:2000
Immunohistochemistry
Recommended dilution: 1:50-1:200最佳稀释倍数与浓度应由实验研究人员确认
产品说明
产品背景
Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.Description
Rabbit polyclonal antibody to Antizyme inhibitor 1
Applications
WB, IHC.
Immunogen
Antizyme inhibitor 1 Antibody detects endogenous levels of total Antizyme inhibitor 1.
Reactivity
Human, Mouse, Rat.
可预测：Pig(100%), Bovine(%), Sheep(%), Rabbit(%), Dog(%), Chicken(%), Xenopus(%)
Molecular weight
49.5 kDa; 50kD(Calculated).
Host species
Rabbit
Ig class
Immunogen-specific rabbit IgG
Purification
Antigen affinity purification
Full name
Antizyme inhibitor 1
Synonyms
Antizyme inhibitor 1; AZI; Azin1; AZIN1_HUMAN; OAZI; OAZIN; ODC1L; Ornithine decarboxylase antizyme inhibitor;
Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Swissprot
O14977
产品图片
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Western blot analysis of extracts from various samples, using Antizyme inhibitor 1 Antibody. Lane 1: Myeloma cells, treated with blocking peptide; Lane 2: Myeloma cells; Lane 3: Hela cells; Lane 4: B16F10 cells. |
