G1005 Sodium Nitroprusside 硝普酸钠

Sodium Nitroprusside是血管舒张剂，能促使NO释放于血液中。 
 

常用名
硝普酸钠

英文名
sodium nitroprusside 

别名
硝普酸钠, 硝普钠, Sodium Nitroferricyanide, Ro 21-2498, Nitroprusside Sodium

CAS号
14402-89-2

分子量
261.91800 

密度
1.72

沸点
N/A 

分子式
C5FeN6Na2O

熔点
N/A 

闪点
N/A 

最佳稀释倍数与浓度应由实验研究人员确认

产品背景

Sodium nitroprusside (Ro 21-2498) 是血管舒张剂，能促使 NO 释放于血液中。
 

生物活性
Sodium nitroprusside (Ro 21-2498) is a potent vasodilator working through releasing NO spontaneously in blood. 

体外研究

(In Vitro)Sodium nitroprusside (Ro 21-2498) is a potent vasodilator. Sodium nitroprusside has potent vasodilating effects in arterioles and venules. Sodium nitroprusside breaks down in circulation to release nitric oxide (NO). NO activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. The end result is vascular smooth muscle relaxation, which allow vessels to dilate [1]. Sodium nitroprusside decreases the proliferation of vascular smooth muscle cells [2]. Sodium nitroprusside (5 mg/kg) significantly reduces the intestinal ischemiareperfusion injury as a nitric oxide donor in rats [3].MCE has not independently confirmed the accuracy of these methods. They are for reference only. 

性状
固体 

颜色
Brown to reddish brown 

运输条件
Room temperature in continental US; may vary elsewhere. 

储存方式
4°C, sealed storage, away from moisture and light