PR10004 Mouse VEGF121 Protein

Product Name

Mouse VEGF121 Protein
 

Gene ID

22339
 

SwissProt ID

Q00731
 

Gene Name

VEGFA
 

Alternative Names

VEGFA; VEGF; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF

最佳稀释倍数与浓度应由实验研究人员确认

产品背景

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
 

Research Field

Cardiovascular
 

Product Categories

Protein
 

Host

E-coli
 

Application

Functional Assay
 

Purification

Affinity Purified
 

Conjugation

Unconjugated
 

Modification

His
 

Form

lyophilized
 

Buffer System

0.01M PBS, pH 7.2
 

Storage

Aliquot and store at -80°C for long term. Avoid freeze/thaw cycles.